IBS + GI Disorders + Immunosuppressants (Alosetron, Lubiprostone, Sulfasalazine, Azathioprine, Cyclosporine)
The Digestive System isn’t always a simple “food in, waste out” highway—sometimes it’s a battlefield of spasms, inflammation, immune misfires, and pain that doesn’t match the scans. In this volume, Lucy and her crew enter the Gut Corridor as it shifts between two enemies: dysregulated motility (IBS) and inflammatory immune attacks (IBD/autoimmune GI disorders)—and they learn when the solution is soothing movement… or quieting the immune system itself.
What this book covers (in story form):
IBS + Motility/Secretion Control
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Alosetron (Lotronex) — When diarrhea dominates: how serotonin signaling affects gut motility and secretion, and the serious safety red flags nurses must recognize.
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Lubiprostone (Amitiza) — When constipation dominates: how fluid secretion softens the “traffic jam,” what patients feel, and what teaching prevents quick discontinuation.
Inflammatory GI Disorders
Immunosuppressants for GI-related & Autoimmune Conditions
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Azathioprine (Imuran) — The “immune volume dial”: why it’s used for chronic control, what labs matter, and how infection risk becomes a nursing priority.
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Cyclosporine (Sandimmune) — The immune system “command block”: powerful suppression when inflammation is severe, plus the high-stakes monitoring that keeps patients safe.
You’ll learn through:
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Clear “IBS vs IBD” storytelling so you stop mixing them up under test pressure
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Mechanism-of-action scenes that link:
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gut motility & secretion → diarrhea/constipation patterns
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mucosal inflammation → bleeding, pain, weight loss, fatigue
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immune suppression → infection risk + lab monitoring priorities
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Nursing priorities & safety checks
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when symptoms are expected vs when they’re emergencies
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medication monitoring habits (CBC/LFTs/renal function, vitals, infection screening)
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patient teaching that improves adherence and prevents complications
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Quick-recall panels + mini NCLEX-style checkpoints embedded in the arc